Placental to Fetal Transfer of Mercury and Fetotoxicity.

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Placental to fetal transfer of mercury and fetotoxicity.

Mercury vapor is known penetrate the placental barrier more easily than inorganic mercury. A relative amount of mercury accumulates in the fetus after exposure of pregnant animals to mercury vapor. Mercury concentration in fetal organs is much lower than that in maternal organs except the liver, and fetal liver shows significantly higher mercury concentrations than maternal liver. In fetal live...

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Fetal responses to placental insufficiency: an update.

Disturbance of normal fetal growth can result in a decrease in weight, or altered body proportion at birth. Fetuses that fail to reach their genetically predetermined growth potential due to intrauterine growth restriction (IUGR) following placental insufficiency are at increased risk for adverse short and long term outcomes that can extend all the way into adult life. Because of its diverse im...

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Placental transfer and fetal metabolic effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery.

BACKGROUND Use of ephedrine in obstetric patients is associated with depression of fetal acid-base status. The authors hypothesized that the mechanism underlying this is transfer of ephedrine across the placenta and stimulation of metabolism in the fetus. METHODS A total of 104 women having elective Cesarean delivery under spinal anesthesia randomly received infusion of phenylephrine (100 mic...

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OBJECTIVE To determine placental transfer of ketanserin and to assess the effect of serotonin-2 receptor blockade by ketanserin on serotonin- and phenylephrine-induced vasoconstriction. STUDY DESIGN Five chronically instrumented pregnant ewes at 120 days gestation were injected with 20 mg ketanserin i.v., and fetal and maternal arterial samples were obtained at predetermined intervals to asse...

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ژورنال

عنوان ژورنال: The Tohoku Journal of Experimental Medicine

سال: 2002

ISSN: 0040-8727,1349-3329

DOI: 10.1620/tjem.196.79